Papaver Bracteatum
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''Papaver bracteatum'', also known as the Iranian poppy or Persian poppy and the great scarlet poppy (first described by Dr. N. Saharghi and l. Lalezari nature 213, 1244, 1967 doi:10.1038/2131244a0 ) is a sturdy hardy perennial
poppy A poppy is a flowering plant in the subfamily Papaveroideae of the family Papaveraceae. Poppies are herbaceous plants, often grown for their colourful flowers. One species of poppy, '' Papaver somniferum'', is the source of the narcotic drug o ...
with large deep red flowers up to 8 inches (20 cm) in diameter on stiff stalks up to 4 feet (1.22 metres) high with a prominent black spot near the base of the petals. It is closely related to the commonly cultivated oriental poppy, ''
Papaver orientale ''Papaver orientale'', the Oriental poppy, is a perennial flowering plant native to the Caucasus, northeastern Turkey, and northern Iran. Oriental poppies grow a mound of leaves that are hairy and finely dissected in spring. They gather ...
'' and is sometimes recorded as the varietal form ''Papaver orientale'' var. ''bracteatum''.


Uses

This species is grown to produce
thebaine Thebaine (paramorphine), also known as codeine methyl enol ether, is an opiate alkaloid, its name coming from the Greek Θῆβαι, '' Thēbai'' (Thebes), an ancient city in Upper Egypt. A minor constituent of opium, thebaine is chemically similar ...
, which is commercially converted to codeine and semi-synthetic opiates including
hydrocodone Hydrocodone, also known as dihydrocodeinone, is an opioid used to treat pain and as a cough suppressant. It is taken by mouth. Typically it is dispensed as the combination acetaminophen/hydrocodone or ibuprofen/hydrocodone for pain severe eno ...
,
hydromorphone Hydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid among others, is an opioid used to treat moderate to severe pain. Typically, long-term use is only recommended for pain due to cancer. It may be used by mou ...
,
oxycodone Oxycodone, sold under various brand names such as Roxicodone and OxyContin (which is the extended release form), is a strong, semi-synthetic opioid used medically for treatment of moderate to severe pain. It is highly addictive and a commonly ...
, and
oxymorphone Oxymorphone (sold under the brand names Numorphan and Opana among others) is a highly potent opioid analgesic indicated for treatment of severe pain. Pain relief after injection begins after about 5–10 minutes, after oral administration it beg ...
. ''Papaver bracteatum'' does not contain
morphine Morphine is a strong opiate that is found naturally in opium, a dark brown resin in poppies (''Papaver somniferum''). It is mainly used as a pain medication, and is also commonly used recreationally, or to make other illicit opioids. T ...
, codeine or any other narcotic alkaloids in significant amounts.
Oripavine Oripavine is an opioid and the major metabolite of thebaine. It is the parent compound from which a series of semi-synthetic opioids are derived, which includes the compounds etorphine and buprenorphine. Although its analgesic potency is compar ...
has been reported in minute traces but would not exert a relevant activity. In the
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territori ...
, domestic cultivation of ''P. bracteatum'' was proposed by president
Richard Nixon Richard Milhous Nixon (January 9, 1913April 22, 1994) was the 37th president of the United States, serving from 1969 to 1974. A member of the Republican Party, he previously served as a representative and senator from California and was ...
's
Office of Management and Budget The Office of Management and Budget (OMB) is the largest office within the Executive Office of the President of the United States (EOP). OMB's most prominent function is to produce the president's budget, but it also examines agency programs, pol ...
in the early 1970s as an alternative to Turkish
opium poppies Opium (or poppy tears, scientific name: ''Lachryma papaveris'') is dried latex obtained from the seed capsules of the opium poppy ''Papaver somniferum''. Approximately 12 percent of opium is made up of the analgesic alkaloid morphine, which i ...
, which the administration was attempting to eliminate. This was because ''P. bracteatum'' does not contain
morphine Morphine is a strong opiate that is found naturally in opium, a dark brown resin in poppies (''Papaver somniferum''). It is mainly used as a pain medication, and is also commonly used recreationally, or to make other illicit opioids. T ...
, which is converted to heroin, but is high in
thebaine Thebaine (paramorphine), also known as codeine methyl enol ether, is an opiate alkaloid, its name coming from the Greek Θῆβαι, '' Thēbai'' (Thebes), an ancient city in Upper Egypt. A minor constituent of opium, thebaine is chemically similar ...
for legal codeine production, which was in crisis at the time because of the dwindling Turkish supply. However, US government scientists feared
Bentley compounds The Bentley compounds are a class of semi-synthetic opioids that were first synthesized by K. W. Bentley by Diels-Alder reaction of thebaine with various dienophiles. The compounds are also known as thevinols, orvinols, or bridged oripavine der ...
,
opioid Opioids are substances that act on opioid receptors to produce morphine-like effects. Medically they are primarily used for pain relief, including anesthesia. Other medical uses include suppression of diarrhea, replacement therapy for opioid use ...
s thousands of times more potent than heroin, would replace heroin in the US. The three species of Oriental poppy, ''Papaver orientale'', ''Papaver orientale'' var. ''bracteatum'' and ''Papaver pseudo-orientale'' are thought to be the basis for up to 80 cultivars derived from cross-breeding and used extensively in ornamental gardens in Europe and the United States as well as elsewhere. ''Papaver orientale'' 'Beauty of Livermere' is regarded as so similar to, if not identical with, the wild ''P. bracteatum'' that it may well be a strain of ''P. bracteatum'' or at the very least a complex hybrid derived from it in large part and is now also referred to as P. orientale 'Goliath Group'.


References


External links

{{Taxonbar, from=Q578200 bracteatum